Identification of dihydropyridines that reduce cellular tau levels. - Semantic Scholar

Abstract

A series of dihydropyridines were identified that have an effect on the accumulation of tau, an important target in Alzheimer's disease. The dihydropyridine collection was expanded using the Hantzsch multicomponent reaction to develop preliminary structure-activity relationships.

DOI: 10.1039/c0cc02253e

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