Identification of differentially expressed proteins in human malignant pleural effusions.

@article{Hsieh2006IdentificationOD,
  title={Identification of differentially expressed proteins in human malignant pleural effusions.},
  author={W-Y Hsieh and M Chen and H-T Ho and T-M You and Yin Lu},
  journal={The European respiratory journal},
  year={2006},
  volume={28 6},
  pages={1178-85}
}
A high protein concentration in a pleural effusion makes it more likely to be a malignant than a transudative effusion. However, the variability in protein composition between these two forms of pleural effusion is not well understood. In order to compare their protein compositions, the proteomic profiles of 14 malignant and 13 transudative pleural effusions were studied using two-dimensional gel electrophoresis. Protein spots with differential expression were identified by matrix-assisted… CONTINUE READING

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