Identification of different isoforms of 14-3-3 protein family in human dermal and epidermal layers

@article{Kilani2008IdentificationOD,
  title={Identification of different isoforms of 14-3-3 protein family in human dermal and epidermal layers},
  author={Ruhangiz Taghi Kilani and Abelardo Medina and Alastair Aitken and Reza Jalili and Matthew Carr and Aziz Ghahary},
  journal={Molecular and Cellular Biochemistry},
  year={2008},
  volume={314},
  pages={161-169}
}
We have previously demonstrated a high level of stratifin, also known as 14-3-3 sigma (σ) in differentiated keratinocyte cell lysate and conditioned medium (CM). In this study, we asked the question of whether other 14-3-3 isoforms are expressed in human dermal fibroblasts, keratinocytes, intact dermal and epidermal layers of skin. In order to address this question, total proteins extracted from cultured cells or skin layers were subjected to western blot analysis using seven different primary… CONTINUE READING

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