Identification of dermatophyte species causing onychomycosis and tinea pedis by MALDI-TOF mass spectrometry.

@article{Erhard2008IdentificationOD,
  title={Identification of dermatophyte species causing onychomycosis and tinea pedis by MALDI-TOF mass spectrometry.},
  author={Marcel Erhard and U. -C. Hipler and Anke Burmester and Axel A. Brakhage and Johannes Woestemeyer},
  journal={Experimental dermatology},
  year={2008},
  volume={17 4},
  pages={356-61}
}
Identification of dermatophytes is currently performed based on morphological criteria and is increasingly supported by genomic sequence comparison. The present study evaluates an alternative based on the analysis of clinical fungal isolates by mass spectrometry. Samples originating from skin and nail were characterized morphologically and by sequencing the internal transcribed spacer 1 (ITS1), ITS2 and the 5.8S rDNA regions of the rDNA clusters. In a blind comparative study, samples were… CONTINUE READING
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