Identification of cross‐reaction patterns in allergic contact dermatitis from topical corticosteroids

@article{Coopman1989IdentificationOC,
  title={Identification of cross‐reaction patterns in allergic contact dermatitis from topical corticosteroids},
  author={Serge A. Coopman and H. Degreef and A. Dooms‐goossens},
  journal={British Journal of Dermatology},
  year={1989},
  volume={121}
}
Contact allergy to topical corticosteroids occurs more frequently than previously supposed. Cross‐allergic phenomena are common. On the basis of a review of the literature and our own patch test data on 15 patients, we conclude that positive patchtests to corticosteroids occur approximately six to seven times more frequently in well‐defined groups of structurally‐related substances than between corticosteroids of different groups. An analogous substitution pattern on the steroid D‐ring or the… 
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  • 2011
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The statistical analysis confirms that tixocortol pivalate and hydrocortisone contact allergies are definitely associated, while reactions to budesonide are strongly correlated with the reactions to both the acetonide group and the ester group.
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