Identification of commonly dysregulated genes in colorectal cancer by integrating analysis of RNA-Seq data and qRT-PCR validation

@article{Xiao2015IdentificationOC,
  title={Identification of commonly dysregulated genes in colorectal cancer by integrating analysis of RNA-Seq data and qRT-PCR validation},
  author={Wen Hui Xiao and Xue-ling Qu and Xue Min Li and YI. LAN. SUN and Hai Xia Zhao and Suming Wang and Xian wan Zhou},
  journal={Cancer Gene Therapy},
  year={2015},
  volume={22},
  pages={278-284}
}
The progression of colorectal cancer (CRC) is a multistep process and metastatic CRC is always incurable; consequently, CRC is the leading cause of cancer-related deaths. There is therefore an urgent need for identifying useful biomarkers with enough sensitivity and specificity to detect this disease at early stages, which will significantly reduce the mortality for this malignancy. In this study, we performed an integrating analysis of different RNA-Seq data sets to find new candidate… CONTINUE READING
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