Identification of cold-inducible microRNAs in plants by transcriptome analysis.

@article{Zhou2008IdentificationOC,
  title={Identification of cold-inducible microRNAs in plants by transcriptome analysis.},
  author={Xuefeng Zhou and Guandong Wang and Keita Sutoh and Jian-Kang Zhu and Weixiong Zhang},
  journal={Biochimica et biophysica acta},
  year={2008},
  volume={1779 11},
  pages={780-8}
}
MicroRNAs are approximately 21-nt long, non-coding RNAs that play critical roles in post-transcriptional gene regulation. Even though a large number of miRNAs have been identified, annotating their functions remains a challenge. We develop a computational, transcriptome-based approach to annotating stress-inducible microRNAs in plants. With this approach, we find that nineteen microRNA genes of eleven microRNA families in Arabidopsis thaliana are up-regulated by cold stress. Our experiments… CONTINUE READING
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