Identification of cocaine and its metabolites in urban wastewater and comparison with the human excretion profile in urine.

@article{Castiglioni2011IdentificationOC,
  title={Identification of cocaine and its metabolites in urban wastewater and comparison with the human excretion profile in urine.},
  author={Sara Castiglioni and Renzo Bagnati and Manuela Melis and Deepika Panawennage and Paul Chiarelli and Roberto Fanelli and Ettore Zuccato},
  journal={Water research},
  year={2011},
  volume={45 16},
  pages={5141-50}
}
The most relevant human urinary metabolites of cocaine (nine metabolites) were measured in urban wastewater in Italy and USA. A novel analytical method based on liquid chromatography tandem mass spectrometry allowed the identification of ecgonine, ecgonine methyl ester and the pyrolytic derivatives of cocaine in untreated wastewater. The aim of this study was to verify whether the pattern of cocaine metabolites in wastewater reflected the human excretion profile in urine. The performance of the… CONTINUE READING

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