Identification of chromosomal fusion sites in Arabidopsis mutants using sequential bicolour BAC-FISH.

@article{Mokro2006IdentificationOC,
  title={Identification of chromosomal fusion sites in Arabidopsis mutants using sequential bicolour BAC-FISH.},
  author={Petr Mokro{\vs} and Jan Vrbsk{\'y} and J. a kol. {\vS}irok{\'y}},
  journal={Genome},
  year={2006},
  volume={49 8},
  pages={
          1036-42
        }
}
Double stranded chromosomal breaks are repaired by homologous recombination or nonhomologous end joining (NHEJ). When broken chromosome ends are fused together by NHEJ, the resulting dicentric chromosomes can be detected as anaphase bridges during the subsequent mitosis. Telomeres in the absence of functional telomerase shorten, became unprotected, and are eventually recognized by the cell repair system as double stranded breaks. As result, chromosomes of Arabidopsis thaliana plants that are… CONTINUE READING
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