Identification of chromatin accessibility domains in human breast cancer stem cells

@inproceedings{Hardy2016IdentificationOC,
  title={Identification of chromatin accessibility domains in human breast cancer stem cells},
  author={Kristine Hardy and F. Wu and W. Tu and Anjum Zafar and T. Boulding and Robert McCuaig and C. R. Sutton and Angelo Theodoratos and Suresh Ranga Rao},
  booktitle={Nucleus},
  year={2016}
}
Epithelial-to-mesenchymal transition (EMT) is physiological in embryogenesis and wound healing but also associated with the formation of cancer stem cells (CSCs). Many EMT signaling pathways are implicated in CSC formation, but the precise underlying mechanisms of CSC formation remain elusive. We have previously demonstrated that PKC is critical for EMT… CONTINUE READING