Identification of chemicals and their metabolites from PHY906, a Chinese medicine formulation, in the plasma of a patient treated with irinotecan and PHY906 using liquid chromatography/tandem mass spectrometry (LC/MS/MS).

@article{Zhang2010IdentificationOC,
  title={Identification of chemicals and their metabolites from PHY906, a Chinese medicine formulation, in the plasma of a patient treated with irinotecan and PHY906 using liquid chromatography/tandem mass spectrometry (LC/MS/MS).},
  author={Wei Zhang and Muhammad Wasif Saif and Ginger E. Dutschman and Xin Li and Wing Yee Lam and Scott Bussom and Zaoli Jiang and Min Ye and Edward Chu and Yung-chi Cheng},
  journal={Journal of chromatography. A},
  year={2010},
  volume={1217 37},
  pages={
          5785-93
        }
}
  • Wei Zhang, Muhammad Wasif Saif, +7 authors Yung-chi Cheng
  • Published in Journal of chromatography. A 2010
  • Chemistry, Medicine
  • Traditional Chinese Medicine (TCM) is increasingly being used in combination with Western medicine. In general, TCM is comprised of multiple components in sharp contrast to Western medicine, where a single active chemical is used. Presently, there are no well-established standards for most of the chemical compounds of TCM and their respective metabolites. Moreover, there are no formal analytical methods for the identification of these chemicals, especially in trace amounts. The ability to… CONTINUE READING

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