Identification of causative chemicals of allergic contact dermatitis using a combination of patch testing in patients and chemical analysis. Application to cases from rubber footwear.

@article{Kaniwa1994IdentificationOC,
  title={Identification of causative chemicals of allergic contact dermatitis using a combination of patch testing in patients and chemical analysis. Application to cases from rubber footwear.},
  author={Masaaki Kaniwa and Kazuo Isama and Akitada Nakamura and H Kantoh and Manabu Itoh and Keita Miyoshi and Shukuko Saito and Mineo Shono},
  journal={Contact dermatitis},
  year={1994},
  volume={30 1},
  pages={26-34}
}
5 cases of allergic contact dermatitis from rubber footwear were investigated by a combination of patch testing in patients and chemical analysis of causative rubber products. Our studies revealed 2-mercaptobenzothiazole (MBT) and benzothiazyl disulfide (MBTS) (typical allergenic accelerators) as causative chemicals in 3 cases from children's rubber shoes, ladies' rubber boots and ladies' canvas shoes. These 3 patients reacted to mercaptobenzothiazole-type accelerators including MBT and MBTS… CONTINUE READING

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