Identification of breast cancer peptide epitopes presented by HLA-A*0201.

  title={Identification of breast cancer peptide epitopes presented by HLA-A*0201.},
  author={Oriana E. Hawkins and Rodney S Vangundy and Annette Marie Eckerd and Wilfried Bardet and Rico Buchli and Jon Weidanz and William H. Hildebrand},
  journal={Journal of proteome research},
  volume={7 4},
Cellular immune mechanisms detect and destroy cancerous and infected cells via the human leukocyte antigen (HLA) class I molecules that present peptides of intracellular origin on the surface of all nucleated cells. The identification of novel, tumor-specific epitopes is a critical step in the development of immunotherapeutics for breast cancer. To directly… CONTINUE READING