Identification of biomarkers for breast cancer in nipple aspiration and ductal lavage fluid.

  title={Identification of biomarkers for breast cancer in nipple aspiration and ductal lavage fluid.},
  author={Jinong Li and Jing Zhao and Xiaodong Yu and Julie Lange and Henry Mark Kuerer and Savitri Krishnamurthy and Eric Schilling and Seema A Khan and Saraswati V. Sukumar and Daniel Wai-Tin Chan},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  volume={11 23},
PURPOSE To establish a comprehensive proteomic approach for biomarker discovery and validation in breast fluid. EXPERIMENTAL DESIGN A total of 95 specimens from three institutions were used including 10 nipple aspiration fluid (5 stage I/II cancerous breasts and 5 age-matched healthy controls), 42 ductal lavage fluid from 14 patients with unilateral stage I/II cancer (25 from 9 cancerous breasts and 17 from 7 contralateral breasts), and 42 ductal lavage fluid from 14 high-risk women (multiple… CONTINUE READING


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