Identification of bacterial small non-coding RNAs: experimental approaches.

@article{Altuvia2007IdentificationOB,
  title={Identification of bacterial small non-coding RNAs: experimental approaches.},
  author={Shoshy Altuvia},
  journal={Current opinion in microbiology},
  year={2007},
  volume={10 3},
  pages={257-61}
}
Almost 140 bacterial small RNAs (sRNAs; sometimes referred to as non-coding RNAs) have been discovered in the past six years. The majority of these sRNAs were discovered in Escherichia coli, and a smaller subset was characterized in other bacteria, many of which were pathogenic. Many of these genes were identified as a result of systematic screens using computational prediction of sRNAs and experimental-based approaches, including microarray and shotgun cloning. A smaller number of sRNAs were… CONTINUE READING
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