Identification of bacteria using tandem mass spectrometry combined with a proteome database and statistical scoring.

@article{Dworzanski2004IdentificationOB,
  title={Identification of bacteria using tandem mass spectrometry combined with a proteome database and statistical scoring.},
  author={Jacek P. Dworzanski and A. Peter Snyder and Rui Chen and H Zhang and D. Wishart and Liang Li},
  journal={Analytical chemistry},
  year={2004},
  volume={76 8},
  pages={2355-66}
}
Detection and identification of pathogenic bacteria and their protein toxins play a crucial role in a proper response to natural or terrorist-caused outbreaks of infectious diseases. The recent availability of whole genome sequences of priority bacterial pathogens opens new diagnostic possibilities for identification of bacteria by retrieving their genomic or proteomic information. We describe a method for identification of bacteria based on tandem mass spectrometric (MS/MS) analysis of… CONTINUE READING