Identification of anxiolytic ingredients in ginseng root using the elevated plus-maze test in mice.

@article{Carr2006IdentificationOA,
  title={Identification of anxiolytic ingredients in ginseng root using the elevated plus-maze test in mice.},
  author={Mellisa N Carr and Naoko Bekku and Hiroyuki Yoshimura},
  journal={European journal of pharmacology},
  year={2006},
  volume={531 1-3},
  pages={
          160-5
        }
}
Ginseng root has been widely used for the management of anxiety and emotional instability, but there is little experimental evidence supporting these clinical applications. We pharmacologically identified the anxiolytic components in ginseng root, using the elevated plus-maze test. Male ICR albino mice and the following drugs were used: diazepam (0.5, 1 and 1.5 mg/kg, p.o.); red ginseng powder (300, 600 and 1200 mg/kg, p.o.); crude saponin and non-saponin ginseng fractions (50, 100 and 200 mg… CONTINUE READING

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