Identification of antibacterial and antifungal pharmacophore sites for potent bacteria and fungi inhibition: indolenyl sulfonamide derivatives.

@article{Chohan2010IdentificationOA,
  title={Identification of antibacterial and antifungal pharmacophore sites for potent bacteria and fungi inhibition: indolenyl sulfonamide derivatives.},
  author={Zahid Hussain Chohan and Moulay H. Youssoufi and Aliasghar Jarrahpour and Taibi ben Hadda},
  journal={European journal of medicinal chemistry},
  year={2010},
  volume={45 3},
  pages={
          1189-99
        }
}
Synthesis of seven new indolenyl sulfonamides, have been prepared by the condensation reaction of indole-3-carboxaldehyde with different sulfonamides such as, sulphanilamide, sulfaguanidine, sulfathiazole, sulfamethoxazole, sulfisoxazole, sulfadiazine and sulfamethazine. These synthesized compounds have been used as potential ligands for complexation with some selective divalent transition metal ions (cobalt, copper, nickel & zinc). Structure of the synthesized ligands has been deduced from… CONTINUE READING
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