Identification of ancient remains through genomic sequencing.

@article{Blow2008IdentificationOA,
  title={Identification of ancient remains through genomic sequencing.},
  author={Matthew J. Blow and Tao Zhang and Tanja Woyke and Camilla F Speller and Andrei Krivoshapkin and Dongya Y. Yang and Anatoly P. Derevianko and Edward M. Rubin},
  journal={Genome research},
  year={2008},
  volume={18 8},
  pages={1347-53}
}
Studies of ancient DNA have been hindered by the preciousness of remains, the small quantities of undamaged DNA accessible, and the limitations associated with conventional PCR amplification. In these studies, we developed and applied a genomewide adapter-mediated emulsion PCR amplification protocol for ancient mammalian samples estimated to be between 45,000 and 69,000 yr old. Using 454 Life Sciences (Roche) and Illumina sequencing (formerly Solexa sequencing) technologies, we examined over… CONTINUE READING

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Identification of ancient remains through genomic sequencing

  • J. Blow, Tao Zhang, +5 authors Edward M. Rubin
  • Genome Research
  • 2008

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