Identification of an iron uptake system specific for coprogen and rhodotorulic acid in Escherichia coli K12

@article{Hantke1983IdentificationOA,
  title={Identification of an iron uptake system specific for coprogen and rhodotorulic acid in Escherichia coli K12},
  author={Klaus Hantke},
  journal={Molecular and General Genetics MGG},
  year={1983},
  volume={191},
  pages={301-306}
}
With the lac operon fusion technique, mutants were isolated in two genes that specify two outer membrane proteins designated FhuE (76 K) and Fiu (83 K). The synthesis of both proteins was increased under low iron growth conditions. The FhuE-protein was shown to be necessary for iron uptake via coprogen, an iron chelator produced by certain fungi, e.g. Neurospora crassa. In addition to fhueE the genes fhuCDB, tonB and exbB were necessary for iron coprogen uptake. The gene fhuE was mapped between… CONTINUE READING