Identification of an evx1-Dependent Joint-Formation Pathway during FIN Regeneration

@inproceedings{Ton2013IdentificationOA,
  title={Identification of an evx1-Dependent Joint-Formation Pathway during FIN Regeneration},
  author={Quynh V. Ton and M Kathryn Iovine},
  booktitle={PloS one},
  year={2013}
}
Joints are essential for skeletal flexibly and form, yet the process underlying joint morphogenesis is poorly understood. Zebrafish caudal fins are comprised of numerous segmented bony fin rays, where growth occurs by the sequential addition of new segments and new joints. Here, we evaluate joint gene expression during fin regeneration. First, we identify three genes that influence joint formation, evx1, dlx5a, and mmp9. We place these genes in a common molecular pathway by evaluating both… CONTINUE READING
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