Identification of an error in the tryptophan → niacin pathway in carriers of some dermatoses conditioned or aggravated by sunlight


The study of the tryptophan→niacin pathway showed a defect of the kynureninase activity at the level of the 3-hydroxykynurenine→3-hydroxyanthranilic acid step in a series of present acquired pellagra carriers (23) and in 5 of a series of 12 chronic erythematodes carriers. The same defect, associated with a deficit of the kynureninase activity also at the… (More)
DOI: 10.1007/BF00520090

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