Identification of an enzymatically formed glutathione conjugate of the cyanobacterial hepatotoxin microcystin-LR: the first step of detoxication.

@article{Pflugmacher1998IdentificationOA,
  title={Identification of an enzymatically formed glutathione conjugate of the cyanobacterial hepatotoxin microcystin-LR: the first step of detoxication.},
  author={Stephan Pflugmacher and Claudia Wiegand and Axel Oberemm and Kenneth A. Beattie and Eberhard Krause and Geoffrey A. Codd and Christian E. W. Steinberg},
  journal={Biochimica et biophysica acta},
  year={1998},
  volume={1425 3},
  pages={527-33}
}
Cyanobacterial toxins have adverse effects on mammals, birds and fish and are being increasingly recognised as a potent stress factor and health hazard factor in aquatic ecosystems. Microcystins, cyclic heptapeptides and a main group of the cyanotoxins are mainly retained within the producer cells during cyanobacterial bloom development. However, these toxins are released into the surrounding medium by senescence and lysis of the blooms. Any toxin present could then come into contact with a… CONTINUE READING
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