Identification of an endogenous plasmid in Dictyostelium discoideum.

  title={Identification of an endogenous plasmid in Dictyostelium discoideum.},
  author={Birgit A. Metz and Thomas E. Ward and Dennis L. Welker and Keith L. Williams},
  journal={The EMBO journal},
  volume={2 4},
A plasmid has been discovered in a strain of the eukaryote, Dictyostelium discoideum, which has an unstable, non-chromosomal, cobalt resistance phenotype. The plasmid, termed Ddp1, is 13.5 kbp in size and is found in the nucleus. It has an A-T content typical of Dictyostelium DNA as judged by its restriction enzyme digestion pattern, and it is not related to either mitochondrial or ribosomal DNA. Similar or identical plasmids have been found in two original, cobalt-sensitive, isolates, NC4 and… CONTINUE READING