Identification of an anti-MRSA dihydrofolate reductase inhibitor from a diversity-oriented synthesis.

@article{Wyatt2008IdentificationOA,
  title={Identification of an anti-MRSA dihydrofolate reductase inhibitor from a diversity-oriented synthesis.},
  author={E. Wyatt and W. R. Galloway and Gemma L. Thomas and M. Welch and O. Loiseleur and A. Plowright and D. R. Spring},
  journal={Chemical communications},
  year={2008},
  volume={40},
  pages={
          4962-4
        }
}
The screening of a diversity-oriented synthesis library followed by structure-activity relationship investigations have led to the discovery of an anti-MRSA agent which operates as an inhibitor of Staphylococcus aureus dihydrofolate reductase. 
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