Identification of an animal omega-3 fatty acid desaturase by heterologous expression in Arabidopsis.

@article{Spychalla1997IdentificationOA,
  title={Identification of an animal omega-3 fatty acid desaturase by heterologous expression in Arabidopsis.},
  author={James P. Spychalla and Anthony J. Kinney and John Browse},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1997},
  volume={94 4},
  pages={1142-7}
}
In animals, fatty acid desaturases catalyze key reactions in the synthesis of arachidonic acid and other polyunsaturated fatty acids. A search of the Caenorhabditis elegans DNA databases, using the sequences of Arabidopsis genes, identified several putative desaturases. Here we describe the characterization of the first of these genes, fat-1. The predicted protein encoded by a fat-1 cDNA showed 32-35% identity with both FAD2 and FAD3 of Arabidopsis. When expressed in transgenic plants, fat-1… CONTINUE READING
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