Identification of an RNA-silencing suppressor in the genome of Grapevine virus A.

@article{Zhou2006IdentificationOA,
  title={Identification of an RNA-silencing suppressor in the genome of Grapevine virus A.},
  author={Zhao Sh ng Zhou and Michela Dell'Orco and Pasquale Saldarelli and Camilla Turturo and Angelantonio Minafra and Giovanni Paolo Martelli},
  journal={The Journal of general virology},
  year={2006},
  volume={87 Pt 8},
  pages={2387-95}
}
Higher plants use post-transcriptional gene silencing (PTGS), an RNA-degradation system, as a defence mechanism against viral infections. To counteract this, plant viruses encode and express PTGS suppressor proteins. Four of the five proteins encoded by the Grapevine virus A (GVA) genome were screened using a green fluorescent protein (GFP)-based transient expression assay, and the expression product of ORF5 (protein p10) was identified as a suppressor of silencing. ORF5 p10 suppressed local… CONTINUE READING

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