Identification of an Intrinsic Determinant Critical for Maspin Subcellular Localization and Function


Maspin, a multifaceted tumor suppressor, belongs to the serine protease inhibitor superfamily, but only inhibits serine protease-like enzymes such as histone deacetylase 1 (HDAC1). Maspin is specifically expressed in epithelial cells and it is differentially regulated during tumor progression. A new emerging consensus suggests that a shift in maspin… (More)
DOI: 10.1371/journal.pone.0074502


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Citations per Year

Citation Velocity: 18

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