Identification of an IL-8 homolog in lamprey (Lampetra fluviatilis): early evolutionary divergence of chemokines.

@article{Najakshin1999IdentificationOA,
  title={Identification of an IL-8 homolog in lamprey (Lampetra fluviatilis): early evolutionary divergence of chemokines.},
  author={Alexander M. Najakshin and Ludmila V. Mechetina and Boris Y. Alabyev and Alexander V. Taranin},
  journal={European journal of immunology},
  year={1999},
  volume={29 2},
  pages={375-82}
}
Subtractive hybridization was used to study river lamprey (Lampetra fluviatilis) leukocyte-specific cDNA. A clone representing the most abundant component (12%) of the leukocyte library subtracted with liver cDNA was isolated and characterized. The cDNA encodes a presumably secreted polypeptide of 101 residues. The 3' untranslated region of the cDNA contains motifs characteristic of the transiently expressing genes. Comparison of the deduced amino acid sequence with known protein sequences… CONTINUE READING
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