Identification of a vaginal pacemaker: An immunohistochemical and morphometric study

  title={Identification of a vaginal pacemaker: An immunohistochemical and morphometric study},
  author={A. Shafik and O. El Sibai and I. Shafik},
  journal={Journal of Obstetrics and Gynaecology},
  pages={485 - 488}
Summary Vaginal electric waves spread caudally in the vagina. We investigated the hypothesis that electric waves originate from a centre of interstitial cells of Cajal (ICCs) in the proximal vagina. Specimens (0.75 × 0.75 cm) were obtained from the vaginal walls of 23 cadavers (age 38.2 ± 10.2 years). Sections were prepared for immunohistochemical investigations using the specific ICC marker, C-kit. Morphometric studies for image analysis using a Leica imaging system were performed. C-kit… Expand
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