Identification of a unique erythroleukemia-associated retroviral gp70 expressed during early stages of normal erythroid differentiation

Abstract

Late in the course of Friend virus (FV)-induced erythroleukemia, leukemic spleen cells express a cell surface retroviral gp70 envelope protein not detected during the early proliferative phase of the disease. Characterization of this gp70 revealed it was unrelated to the input Friend murine leukemia virus (F-MuLV), but antigenically similar to a unique… (More)

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