Identification of a transforming growth factor alpha-like molecule in human seminal plasma.

@article{Yie1994IdentificationOA,
  title={Identification of a transforming growth factor alpha-like molecule in human seminal plasma.},
  author={Shang-Mian Yie and Derek K. Lobb and David A. Clark and Edward V. Younglai},
  journal={Fertility and sterility},
  year={1994},
  volume={61 1},
  pages={129-35}
}
OBJECTIVE To characterize the putative seminal growth promoting factor serendipitously observed when human seminal plasma was analyzed for bioactive FSH. DESIGN A pool of human seminal plasma was subjected to sequential Sephadex G-75 (superfine) chromatography and high-performance size exclusion liquid chromatography. The fractions were tested for mitogenic activity using a rat granulosa cell assay and normal rat kidney (NRK) cells. Properties of the factor were established and… CONTINUE READING