Identification of a strategic brain network underlying processing speed deficits in vascular cognitive impairment

  title={Identification of a strategic brain network underlying processing speed deficits in vascular cognitive impairment},
  author={M. Duering and M. Gonik and R. Malik and Nikola Zieren and S. Reyes and E. Jouvent and D. Herv{\'e} and A. Gschwendtner and C. Opherk and H. Chabriat and M. Dichgans},
  • M. Duering, M. Gonik, +8 authors M. Dichgans
  • Published 2013
  • Psychology, Medicine, Computer Science
  • NeuroImage
  • Patients with vascular cognitive impairment (VCI) commonly exhibit deficits in processing speed. This has been attributed to a disruption of frontal-subcortical neuronal circuits by ischemic lesions, but the exact mechanisms and underlying anatomical structures are poorly understood. We set out to identify a strategic brain network for processing speed by applying graph-based data-mining techniques to MRI lesion maps from patients with small vessel disease. We studied 235 patients with CADASIL… CONTINUE READING
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