Identification of a strain-specific malarial antigen exposed on the surface of Plasmodium falciparum-infected erythrocytes

@article{Leech1984IdentificationOA,
  title={Identification of a strain-specific malarial antigen exposed on the surface of Plasmodium falciparum-infected erythrocytes},
  author={J. Leech and J. Barnwell and L. Miller and R. Howard},
  journal={The Journal of Experimental Medicine},
  year={1984},
  volume={159},
  pages={1567 - 1575}
}
  • J. Leech, J. Barnwell, +1 author R. Howard
  • Published 1984
  • Medicine, Biology
  • The Journal of Experimental Medicine
  • We have identified strain-specific antigens with Camp and St. Lucia strains of P. falciparum of Mr approximately 285,000 and approximately 260,000, respectively. These strain-specific antigens were metabolically labeled with radioactive amino acids, indicating that they were of parasite origin rather than altered host components. These proteins had the properties of a molecule exposed on the surface of infected erythrocytes (IE). First, the proteins are accessible to lactoperoxidase-catalyzed… CONTINUE READING
    404 Citations
    Two approximately 300 kilodalton Plasmodium falciparum proteins at the surface membrane of infected erythrocytes.
    • 122
    Identification and Characterization of the Antigens Expressed On the Surface of Human Erythrocytes Infected With Plasmodium falciparum
    • 1
    Knob-positive and knob-negative Plasmodium falciparum differ in expression of a strain-specific malarial antigen on the surface of infected erythrocytes
    • 162
    • PDF
    Variable antigen associated with the surface of erythrocytes infected with mature stages of Plasmodium falciparum.
    • 85

    References

    SHOWING 1-10 OF 12 REFERENCES
    Antigenic variation of Plasmodium knowlesi malaria: identification of the variant antigen on infected erythrocytes.
    • R. Howard, J. Barnwell, V. Kao
    • Biology, Medicine
    • Proceedings of the National Academy of Sciences of the United States of America
    • 1983
    • 126
    • PDF
    Plasmodium falciparum malaria. Ultrastructure of parasitized erythrocytes in cardiac vessels.
    • S. Luse, L. Miller
    • Biology, Medicine
    • The American journal of tropical medicine and hygiene
    • 1971
    • 331
    Human malaria parasites in continuous culture.
    • 6,700
    Maturation of the head of bacteriophage T4. I. DNA packaging events.
    • 3,183
    Integral membrane protein interaction with Triton cytoskeletons of erythrocytes.
    • M. Sheetz
    • Chemistry, Medicine
    • Biochimica et biophysica acta
    • 1979
    • 143
    Isolation and characterization of human erythrocytes infected with the malarial parasite , Plasmodium falciparum
    • Proc . Natl . Acad . Sci . USA .
    • 1983