Identification of a strain-specific malarial antigen exposed on the surface of Plasmodium falciparum-infected erythrocytes

  title={Identification of a strain-specific malarial antigen exposed on the surface of Plasmodium falciparum-infected erythrocytes},
  author={J. Leech and J. Barnwell and L. Miller and R. Howard},
  journal={The Journal of Experimental Medicine},
  pages={1567 - 1575}
  • J. Leech, J. Barnwell, +1 author R. Howard
  • Published 1984
  • Medicine, Biology
  • The Journal of Experimental Medicine
  • We have identified strain-specific antigens with Camp and St. Lucia strains of P. falciparum of Mr approximately 285,000 and approximately 260,000, respectively. These strain-specific antigens were metabolically labeled with radioactive amino acids, indicating that they were of parasite origin rather than altered host components. These proteins had the properties of a molecule exposed on the surface of infected erythrocytes (IE). First, the proteins are accessible to lactoperoxidase-catalyzed… CONTINUE READING
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