Identification of a strain-specific malarial antigen exposed on the surface of Plasmodium falciparum-infected erythrocytes

@article{Leech1984IdentificationOA,
  title={Identification of a strain-specific malarial antigen exposed on the surface of Plasmodium falciparum-infected erythrocytes},
  author={Jeanette Leech and John W. Barnwell and Louis H. Miller and Russell John Howard},
  journal={The Journal of Experimental Medicine},
  year={1984},
  volume={159},
  pages={1567 - 1575}
}
We have identified strain-specific antigens with Camp and St. Lucia strains of P. falciparum of Mr approximately 285,000 and approximately 260,000, respectively. These strain-specific antigens were metabolically labeled with radioactive amino acids, indicating that they were of parasite origin rather than altered host components. These proteins had the properties of a molecule exposed on the surface of infected erythrocytes (IE). First, the proteins are accessible to lactoperoxidase-catalyzed… CONTINUE READING

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