Identification of a spectrin-like protein in nonerythroid cells.

  title={Identification of a spectrin-like protein in nonerythroid cells.},
  author={S. Goodman and I. Zagon and R. Kulikowski},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={78 12},
We have demonstrated the existence of a spectrin-like protein in a variety of nonerythroid cultured cells. Indirect immunofluorescence studies with monospecific antispectrin IgG indicated the presence of proteins that have common antigenic determinants to spectrin in embryonic chicken cardiac myocytes, mouse fibroblast lines (3T3, simian virus 4-transformed 3T3), and rat hepatoma lines (HTC, HMOA). Two spectrin-like peptides of 240,000 and 230,000 daltons were immunoprecipitated from octyl… Expand
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