Identification of a specific Mycobacterium tuberculosis protein able to activate T lymphocytes.

@article{Vismara1991IdentificationOA,
  title={Identification of a specific Mycobacterium tuberculosis protein able to activate T lymphocytes.},
  author={D Vismara and Marco Favaro and Francesca V Mariani and Enza Piccolella and Vittorio Colizzi},
  journal={Annali dell'Istituto superiore di sanita},
  year={1991},
  volume={27 1},
  pages={21-6}
}
The recent advances in the field of immunology and molecular biology allow to consider not distant the identification of protective antigens to be used in new prophilactic and diagnostic tools. In our laboratory we have analysed a M. tuberculosis expression library by murine monoclonal antibodies, human sera and human T lymphocytes. We have identified a 35 Kd protein present only on the M. tuberculosis complex (M. tuberculosis, M. bovis, M. africanum). This 35 Kd protein is also detected, by… CONTINUE READING