Identification of a single killer immunoglobulin-like receptor (KIR) gene in the porcine leukocyte receptor complex on chromosome 6q

@article{Sambrook2006IdentificationOA,
  title={Identification of a single killer immunoglobulin-like receptor (KIR) gene in the porcine leukocyte receptor complex on chromosome 6q},
  author={Jennifer G. Sambrook and Harminder Sehra and Penny C. Coggill and Sean J. Humphray and Sophie Palmer and Sarah Sims and H Takamatsu and Thomas M. Wileman and Alan L. Archibald and Stephan Beck},
  journal={Immunogenetics},
  year={2006},
  volume={58},
  pages={481-486}
}
Human killer immunoglobulin-like receptors (KIR) are expressed on natural killer (NK) cells and are involved in their immunoreactivity. While KIR with a long cytoplasmic tail deliver an inhibitory signal when bound to their respective major histocompatibility complex class I ligands, KIR with a short cytoplasmic tail can activate NK responses. The expansion… CONTINUE READING