Identification of a signal sequence necessary for the unconventional secretion of Engrailed homeoprotein

@article{Joliot1998IdentificationOA,
  title={Identification of a signal sequence necessary for the unconventional secretion of Engrailed homeoprotein},
  author={Alain Henri Joliot and Alexis Maizel and Dan Rosenberg and Alain Trembleau and St{\'e}phane Dupas and Michel Volovitch and Alain Prochiantz},
  journal={Current Biology},
  year={1998},
  volume={8},
  pages={856-863}
}
BACKGROUND Engrailed-1 and Engrailed-2 are homeoproteins--transcription factors implicated in the morphogenesis of discrete structures. Engrailed proteins have a role in patterning the midbrain-hindbrain region and are expressed in the nuclei of rat embryo midbrain-hindbrain cells. We have previously found that both endogenous and exogenously expressed… CONTINUE READING