Identification of a region required for subtype-specific agonist-induced sequestration of the m2 muscarinic acetylcholine receptor.

Abstract

When the m1 and m2 muscarinic acetylcholine receptors are transiently expressed in JEG-3 cells, the m2, but not the m1, receptor undergoes agonist-induced sequestration. Both receptors exhibit internalization when expressed in Y1 cells. These results suggest that the m1 and m2 receptors use distinct cellular mechanisms or pathways for agonist-induced… (More)

Topics

Cite this paper

@article{Goldman1996IdentificationOA, title={Identification of a region required for subtype-specific agonist-induced sequestration of the m2 muscarinic acetylcholine receptor.}, author={Peter Goldman and M L Schlador and Robert Shapiro and Noel Nathanson}, journal={The Journal of biological chemistry}, year={1996}, volume={271 8}, pages={4215-22} }