Identification of a putative shared epitope between Coxsackie virus B4 and alpha cardiac myosin heavy chain.


Molecular mimicry is an important postulated mechanism for autoimmunity in viral myocarditis. The 356-1 monoclonal antibody neutralizes Coxsackie virus B4 by binding to the VP1 protein and cross-reacts with mouse alpha cardiac myosin heavy chain. We used this monoclonal antibody to screen a lambda gt11 expression library made from CD-1 mouse hearts. Of the… (More)


Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.