Identification of a putative precursor to the major surface glycoprotein of Pneumocystis carinii.

@article{Sunkin1998IdentificationOA,
  title={Identification of a putative precursor to the major surface glycoprotein of Pneumocystis carinii.},
  author={Susan Sunkin and Michael Linke and Francis X McCormack and Peter D. Walzer and James R. Stringer},
  journal={Infection and immunity},
  year={1998},
  volume={66 2},
  pages={741-6}
}
The major surface glycoprotein (MSG) of Pneumocystis carinii f. sp. carinii is a family of proteins encoded by a family of heterogeneous genes. Messenger RNAs encoding different MSGs each begin with the same 365-bp sequence, called the Upstream Conserved Sequence (UCS), which is in frame with the contiguous MSG sequence. The UCS contains several potential start sites for translation. To determine if translation of MSG mRNAs begins in the UCS, polyclonal antiserum was raised against the 123… CONTINUE READING
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