Identification of a protein encoded by the vpu gene of HIV-1

  title={Identification of a protein encoded by the vpu gene of HIV-1},
  author={{\'E}ric A Cohen and Ernest F. Terwilliger and Joseph Sodroski and William A. Haseltine},
Human immunodeficiency virus 1 (HIV-1) is the aetiological agent of AIDS1–3. The virus establishes lytic, latent and non-cytopathic productive infection in cells in culture4,5. The complexity of virus‐host cell interaction is reflected in the complex organization of the viral genome6–9. In addition to the genes that encode the virion capsid and envelope proteins and the enzymes required for proviral synthesis and integration common to all retroviruses, HIV-1 is known to encode at least four… CONTINUE READING


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