Identification of a proctolin preprohormone gene (Proct) of Drosophila melanogaster: expression and predicted prohormone processing.

@article{Taylor2004IdentificationOA,
  title={Identification of a proctolin preprohormone gene (Proct) of Drosophila melanogaster: expression and predicted prohormone processing.},
  author={Christine A M Taylor and Asa M E Winther and Richard J Siviter and Alan D. Shirras and R Elwyn Isaac and Dick R N{\"a}ssel},
  journal={Journal of neurobiology},
  year={2004},
  volume={58 3},
  pages={379-91}
}
Proctolin was the first insect neuropeptide to be sequenced and has been the subject of many physiological and pharmacological studies in insects and crustaceans. We have identified a Drosophila gene (CG7105, Proct) encoding a precursor protein containing the neuropeptide proctolin (RYLPT). In situ hybridization with a riboprobe to the Proct gene revealed a distribution of transcript in neurons of the larval central nervous system (CNS) matching that seen with antiserum to proctolin. An… CONTINUE READING