Identification of a peptide inhibitor of the RPM-1 · FSN-1 ubiquitin ligase complex.

Abstract

The Pam/Highwire/RPM-1 (PHR) proteins include: Caenorhabditis elegans RPM-1 (Regulator of Presynaptic Morphology 1), Drosophila Highwire, and murine Phr1. These important regulators of neuronal development function in synapse formation, axon guidance, and axon termination. In mature neurons the PHR proteins also regulate axon degeneration and regeneration… (More)
DOI: 10.1074/jbc.M114.614065

Topics

7 Figures and Tables

Cite this paper

@article{Sharma2014IdentificationOA, title={Identification of a peptide inhibitor of the RPM-1 · FSN-1 ubiquitin ligase complex.}, author={Jaiprakash Sharma and Scott Thomas Baker and Shane M. Turgeon and Allison M. Gurney and Karla Opperman and Brock Grill}, journal={The Journal of biological chemistry}, year={2014}, volume={289 50}, pages={34654-66} }