Identification of a pathogen-binding lectin in salmon serum.

  title={Identification of a pathogen-binding lectin in salmon serum.},
  author={Kathryn Vanya Ewart and Stewart C. Johnson and Neil W. Ross},
  journal={Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology},
  volume={123 1},
A mannose-binding lectin was isolated from the blood serum of Atlantic salmon (Salmo salar). Analysis by sodium dodecyl sulfate-polyacrylamide gel electrophoresis under reducing and non-reducing conditions revealed a multimeric structure composed of 17000 Mr subunits. Hexosamine analysis and glycosidase digestion showed that the lectin is not glycosylated and amino acid analysis revealed no unusual compositional features. Using ruthenium red staining, the lectin was shown to bind Ca2+ ions. N… CONTINUE READING