Identification of a novel protein kinase A anchoring protein that binds both type I and type II regulatory subunits.

@article{Huang1997IdentificationOA,
  title={Identification of a novel protein kinase A anchoring protein that binds both type I and type II regulatory subunits.},
  author={Lily Jun-shen Huang and Kyle Durick and Joshua A Weiner and Jongsik Chun and Susan S. Taylor},
  journal={The Journal of biological chemistry},
  year={1997},
  volume={272 12},
  pages={8057-64}
}
Compartmentalization of cAMP-dependent protein kinase is achieved in part by interaction with A-kinase anchoring proteins (AKAPs). All of the anchoring proteins identified previously target the kinase by tethering the type II regulatory subunit. Here we report the cloning and characterization of a novel anchoring protein, D-AKAP1, that interacts with the N terminus of both type I and type II regulatory subunits. A novel cDNA encoding a 125-amino acid fragment of D-AKAP1 was isolated from a two… CONTINUE READING

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D-AKAP1, a Novel Protein Kinase A Anchoring Protein

  • I. Boekhoff, S. Schleicher, J. Strotmann, H. Breer
  • Proc. Natl. Acad. Sci. U. S. A
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