Identification of a novel population of adrenal-like cells in the mammalian testis.

@article{Val2006IdentificationOA,
  title={Identification of a novel population of adrenal-like cells in the mammalian testis.},
  author={Pierre Val and Katherine Jeays-Ward and Amanda Swain},
  journal={Developmental biology},
  year={2006},
  volume={299 1},
  pages={250-6}
}
Steroidogenic cells of the adrenal and gonad are thought to be derived from a common primordium that divides into separate tissues during embryogenesis. In this paper, we show that cells with mixed adrenal and Leydig cell properties are found dispersed in the insterstitium of the embryonic and adult mouse testis. They express the adrenal markers Cyp11b1 and Cyp21 and respond to ACTH. Consistent with these properties, we show that the embryonic testis produces the adrenal steroid corticosterone… CONTINUE READING
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