Identification of a novel murine organic anion transporter family member, OAT6, expressed in olfactory mucosa.

@article{Monte2004IdentificationOA,
  title={Identification of a novel murine organic anion transporter family member, OAT6, expressed in olfactory mucosa.},
  author={Julio C. Monte and Megha A. Nagle and Satish A. Eraly and Sanjay K. Nigam},
  journal={Biochemical and biophysical research communications},
  year={2004},
  volume={323 2},
  pages={429-36}
}
The organic anion and cation transporters (OATs and OCTs) are a large family (SLC22) of transmembrane proteins that are able to transport a variety of compounds including drugs, environmental toxins, and endogenous metabolites. OATs are expressed in various tissues, primarily kidney and liver, but also in placenta, small intestine, and choroid plexus, which are all epithelial tissues that transport xenobiotics. The upper airway, particularly the nose, is also a site of frequent exposure to… CONTINUE READING

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