Identification of a novel metallo-β-lactamase VIM-28 located within unusual arrangement of class 1 integron structure in Pseudomonas aeruginosa isolates from Egypt.

@article{ELMAHDY2014IdentificationOA,
  title={Identification of a novel metallo-β-lactamase VIM-28 located within unusual arrangement of class 1 integron structure in Pseudomonas aeruginosa isolates from Egypt.},
  author={TAGHRID S. EL-MAHDY},
  journal={Japanese journal of infectious diseases},
  year={2014},
  volume={67 5},
  pages={382-4}
}
Two multidrug-resistant Pseudomonas aeruginosa strains harboring blaVIM were isolated from a hospital in Egypt and were indistinguishable by pulsed-field gel electrophoresis. Sequence analysis revealed a novel VIM β-lactamase, VIM-28. Additional sequencing of integron revealed that the blaVIM-28 gene cassette had an unusual arrangement of class 1 integron structure, located directly downstream of the integrase gene "intI1" and oriented divergently from it. The new organization of integron also… CONTINUE READING