Identification of a novel leucine-rich repeat protein as a component of flagellar radial spoke in the Ascidian Ciona intestinalis.

@article{Padma2003IdentificationOA,
  title={Identification of a novel leucine-rich repeat protein as a component of flagellar radial spoke in the Ascidian Ciona intestinalis.},
  author={Potturi Padma and Yuhkoh Satouh and Ken-Ichi Wakabayashi and Akiko Hozumi and Yuji Ushimaru and Ritsu Kamiya and Kazuo Inaba},
  journal={Molecular biology of the cell},
  year={2003},
  volume={14 2},
  pages={774-85}
}
Axonemes are highly organized microtubule-based structures conserved in many eukaryotes. In an attempt to study axonemes by a proteomics approach, we selectively cloned cDNAs of axonemal proteins by immunoscreening the testis cDNA library from the ascidian Ciona intestinalis by using an antiserum against whole axonemes. We report here a 37-kDa protein of which cDNA occurred most frequently among total positive clones. This protein, named LRR37, belongs to the class of SDS22+ leucine-rich repeat… CONTINUE READING
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